Search results for " health risks"
showing 5 items of 5 documents
Cytochrome P450 2E1 variable number tandem repeat polymorphisms and health risks: A genotype-phenotype study in cancers associated with drinking and/…
2012
Cytochrome P450 2E1 (CYP2E1) is one of the main enzymes involved in the oxidation of ethanol and in the transformation of a number of potentially dangerous compounds. It has various polymorphic sites, one of which is a variable number tandem repeat (VNTR) polymorphism previously described in the 5'-flanking region. The aim of this study was to investigate the genotype-phenotype association between CYP2E1 VNTR polymorphisms and risky health habits in healthy subjects and to analyze the associations between these polymorphisms with drinking- and/or smoking-related cancers. We analyzed 166 healthy subjects by genotyping for the CYP2E1 VNTR polymorphism associated with drinking and/or smoking h…
Knowledge, risk perception and behaviours in swimming pool users of Palermo city, Sicily
2012
Abstract To assess knowledge, risk perception and behaviours of a sample of swimming pool users in Palermo. A total of 498 subjects were interviewed by self-administered anonymous questionnaire including socio-demographic questions, knowledge/risk perception and behaviours. Overall, 289 subjects (58%) had a mean of 1.9±1.2 healthy behaviours. Age older than 30 years (OR=0.46; 95% CI=0.26–0.81), female sex (OR=0.52; 95% CI=0.35–0.76) and a high knowledge score (OR=0.15; 95% CI=0.03–0.69) were significantly associated with having healthy behaviours in both univariate and multivariate analysis. Unhealthy behaviours can be frequently found in swimming pool bathers and, particularly, in some tar…
The emergence of Vibrio pathogens in Europe : ecology, evolution, and pathogenesis (Paris, 11-12th March 2015)
2015
Global change has caused a worldwide increase in reports of Vibrio-associated diseases with ecosystem-wide impacts on humans and marine animals. In Europe, higher prevalence of human infections followed regional climatic trends with outbreaks occurring during episodes of unusually warm weather. Similar patterns were also observed in Vibrio-associated diseases affecting marine organisms such as fish, bivalves and corals. Basic knowledge is still lacking on the ecology and evolutionary biology of these bacteria as well as on their virulence mechanisms. Current limitations in experimental systems to study infection and the lack of diagnostic tools still prevent a better understanding of Vibrio…
Loss of life expectancy from air pollution compared to other risk factors: a worldwide perspective
2020
Abstract Aims Long-term exposure of humans to air pollution enhances the risk of cardiovascular and respiratory diseases. A novel Global Exposure Mortality Model (GEMM) has been derived from many cohort studies, providing much-improved coverage of the exposure to fine particulate matter (PM2.5). We applied the GEMM to assess excess mortality attributable to ambient air pollution on a global scale and compare to other risk factors. Methods and results We used a data-informed atmospheric model to calculate worldwide exposure to PM2.5 and ozone pollution, which was combined with the GEMM to estimate disease-specific excess mortality and loss of life expectancy (LLE) in 2015. Using this model, …
A CASE STUDY OF THE INDOOR AIR QUALITY IN SCHOOLS BELONGING TO AN AREA OF THE SICILIAN ISLAND INTERESTED BY THE PRESENCE OF PETROCHEMICAL REFINERIES
2021
The indoor environmental quality is a topic particularly relevant for schools; this category of confined environments is, indeed, occupied by subjects (i.e. children), which are thought to be more vulnerable than adults to the negative health effects of poor indoor air quality, and whose learning process has long been recognized to be influenced by the quality of the indoor environment. This paper presents results of a study concerning the inside air quality of schools in four small towns sited in the southern part of Sicily, interested by the presence of a petrochemical refinery in the surrounding territory. The performed analysis made it possible to highlight the main criticalities regard…